Predictable Therapeutic Microswarm Dispersion for Targeted Drug Delivery Application

EasyChair Preprint 8300

Abstract

The magnetic nanoparticles (MNPs) based micronanorobots are emerging drug carriers. Controllability by an external magnetic field is the major advantage of these drug carriers. However, they are facing several challenges including controllability of the individual motion of MNPs under a global magnetic field. The microswarm control where collective MNPs were guided by a magnetic field was proposed as a solution. We have developed a computational platform to predict microswimmers' shape formation and disintegration under different rotating magnetic field conditions. The platform was experimentally validated. The study of the effective parameters shows that independent of any environmental, geometric and process conditions, the dispersion changes are slow, and the dispersion becomes stable after 20 s. The results showed that at a very high and very low frequency, microswarm dispersion does not have high scattering and the final scattering changes are very small.

Keyphrases: Magnetic Nano particles, Targeted drug delivery, micro-robots, separation

@booklet{EasyChair:8300,
  author    = {Kiana Abolfathi and Mohammad Reza Hairi Yazdi and Ali Kafash Hoshiar},
  title     = {Predictable Therapeutic Microswarm Dispersion for Targeted Drug Delivery Application},
  howpublished = {EasyChair Preprint 8300},
  year      = {EasyChair, 2022}}