Download PDFOpen PDF in browserTo Estimate the Minimum Electrical Voltage Treat the Epileptic Event via Deep Brain Stimulation TechniqueEasyChair Preprint 90955 pages•Date: October 24, 2022AbstractBiological Applications require experimentations to make them in practical or clinical use. Simulation modeling efficiently solves reality-based problems and provides the right of simplex systems. Simulation of the reality-based system is preferred before applying any procedure realistically. The response of the system in case of maximum values of stimulus can also be checked through simulation of the desired model. COMSOL (Computer solution of) Multiphysics is a simulation environment which is designed to mimic real world applications. To understand the realistic systems modeling and their response, this study provides the simulation of deep stimulation Deep brain stimulation (DBS) has recently been proven to be an effective therapy for medication-refractory symptoms of Parkinson’s disease. Deep brain stimulation (DBS) is remarkably effective for a range of neurological and psychiatric disorders that have failed pharmacological and cell transplant therapies. Clinical investigations are underway for a variety of other conditions. Yet, the therapeutic mechanisms of action are unknown. In addition, DBS research demonstrates the need to re-consider many hypotheses regarding basal ganglia physiology and pathophysiology such as the notion that increased activity in the globus pallidus internal segment is causal to Parkinson's disease symptoms. Keyphrases: Bain simulations, Parkinson’s disease, basal ganglia, clinical investigators
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