Download PDFOpen PDF in browserFrom Lab-on-a-Chip to Point-of-Care: Microfluidic Technologies Impacting HealthcareEasyChair Preprint 115518 pages•Date: December 17, 2023AbstractMicrofluidic technologies have revolutionized the landscape of healthcare by enabling the development of sophisticated diagnostic tools that bridge the gap between laboratory-based analyses and point-of-care applications. This review explores the transformative journey from lab-on-a-chip platforms to practical point-of-care solutions, highlighting the significant impact of microfluidics on healthcare. The evolution of microfluidic devices from complex laboratory setups to portable, user-friendly systems has accelerated the integration of diagnostic assays into everyday clinical practice. These devices leverage the manipulation of minute fluid volumes within microscale channels to perform diverse functions such as sample preparation, cell sorting, and biochemical analysis with unprecedented precision and efficiency. The integration of microfluidics with other technologies such as biosensors, imaging modalities, and artificial intelligence has further enhanced the sensitivity, specificity, and speed of diagnostic procedures. The shift towards point-of-care applications has brought healthcare closer to the patients, offering rapid and on-the-spot diagnosis, reducing turnaround times, and improving treatment outcomes. Portable microfluidic devices have empowered healthcare providers in resource-limited settings to perform timely and accurate diagnostics, thus addressing global health challenges more effectively. Keyphrases: Microfluidics, Portable devices, diagnostics
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