Navigating the Role of Humanized Mouse and Rat Models in Advancing HIV Research: Bridging in Vitro Studies to Clinical Trials

EasyChair Preprint no. 12460

Abstract

Within the realm of HIV research, humanized mouse and rat models have evolved into essential instruments, serving as vital links between in vitro studies and clinical trials. This article delves into the present state of these models, emphasizing their pivotal roles in exploring preventive and curative strategies against HIV infection and related pathologies. The discourse encompasses diverse methodologies employed for the humanization of these animal models, addresses challenges faced in their utilization, and introduces emerging techniques that hold promise in advancing HIV research. Through a thorough examination of the strengths and limitations inherent in existing models, this article aims to guide researchers toward more effective strategies in the ongoing battle against HIV/AIDS.

Keyphrases: clinical trials, Humanized Mouse, Rat Models

@Booklet{EasyChair:12460,
  author = {Liis Tammik},
  title = {Navigating the Role of Humanized Mouse and Rat Models in Advancing HIV Research: Bridging in Vitro Studies to Clinical Trials},
  howpublished = {EasyChair Preprint no. 12460},

  year = {EasyChair, 2024}}