A Comprehensive Study on Q203-PBTZ169 Interaction and Its Impact on Mycobacterial Infection

EasyChair Preprint 11870

Abstract

This research presents a thorough examination of the interaction between Q203 and PBTZ169 and its consequential impact on mycobacterial infection, particularly focusing on Mycobacterium tuberculosis. Through a series of in vitro and in vivo experiments, this study elucidates the intricate dynamics and potential synergies between these two compounds. The in vitro assessments employ the checkerboard method, elucidating the fractional inhibitory concentration index (FICI) to quantify the interaction effects. Results indicate a synergistic relationship, with the combined action of Q203 and PBTZ169 surpassing individual efficacy, highlighting a promising avenue for tuberculosis treatment.

Keyphrases: Mycobacterium, Q203, Tuberculosis

@booklet{EasyChair:11870,
  author    = {Kurez Oroy and Thomas Jhon},
  title     = {A Comprehensive Study on Q203-PBTZ169 Interaction and Its Impact on Mycobacterial Infection},
  howpublished = {EasyChair Preprint 11870},
  year      = {EasyChair, 2024}}