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Cracking the Code: Identifying Crucial Structural Features in Hsp90 Alpha Inhibitors for Effective Cancer Treatment

EasyChair Preprint 11631

6 pagesDate: December 27, 2023

Abstract

Cancer remains a formidable health challenge, underscoring the urgency to devise innovative therapeutic strategies. Among the potential targets, Hsp90 Alpha emerges as a promising candidate due to its pivotal role in stabilizing several cancer-associated proteins. This research delves into the intricate structural features essential for inhibiting Hsp90 Alpha effectively. Employing consensus pharmacophore modeling, the study illuminates critical lipophilic and hydrogen-bonding domains within inhibitors that demonstrate heightened anti-cancer activity. Such insights pave the way for the development of potent and targeted anti-cancer therapeutics, heralding a promising stride in cancer treatment modalities.

Keyphrases: Inhibitors, cancer, treatment

BibTeX entry
BibTeX does not have the right entry for preprints. This is a hack for producing the correct reference:
@booklet{EasyChair:11631,
  author    = {Kurez Oroy and Herber Schield},
  title     = {Cracking the Code: Identifying Crucial Structural Features in Hsp90 Alpha Inhibitors for Effective Cancer Treatment},
  howpublished = {EasyChair Preprint 11631},
  year      = {EasyChair, 2023}}
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