Download PDFOpen PDF in browserPharmacological Interventions for Persistent Pain Post-Spine Surgery: Novel Therapeutic Targets and Drug Delivery SystemsEasyChair Preprint 1290312 pages•Date: April 4, 2024AbstractPersistent pain following spinal surgery poses significant challenges for patients and clinicians, often requiring multifaceted management strategies. This article explores the landscape of pharmacological interventions for persistent pain post-spine surgery, focusing on novel therapeutic targets and drug delivery systems. Drawing upon recent advancements in pain research and pharmaceutical technology, the article reviews emerging pharmacotherapies targeting specific pain pathways and mechanisms implicated in post-surgical pain. Additionally, it examines innovative drug delivery systems designed to enhance the efficacy and safety of pain medications while minimizing systemic side effects. By synthesizing current research evidence and clinical insights, this article aims to provide a comprehensive overview of novel pharmacological approaches for managing persistent pain post-spine surgery, offering valuable insights for clinicians, researchers, and patients seeking effective pain management strategies in this challenging clinical context. Keyphrases: Pain Post-Spine, Spine surgery, drug delivery systems
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