Nanofibers and Their Applications in Tissue Engineering

EasyChair Preprint 13284

Abstract

One of the primary challenges in the science of tissue engineering is the development of scaffolds that imitate the architecture of tissue at the nanoscale. The potential for creating scaffolds that might be able to fulfill this problem has been substantially expanded by the creation of nanofibers. Currently, electrospinning, self- assembly, and phase separation are the three methods that can be used to create nanofibers. The most extensively researched method among these is electrospinning, which has also shown the most encouraging outcomes in terms of tissue engineering applications. The potential for creating nanofibrous scaffolds has increased thanks to the availability of a variety of organic and synthetic biomaterials, particularly when using the electrospinning technique. Nanofibers were used to create three-dimensional synthetic biodegradable scaffolds that provide an ideal framework for cell adhesion, proliferation, and differentiation. Because of this, nanofibers regardless of how they were made have been used as carriers for the carefully controlled delivery of drugs, proteins, and DNA, as well as scaffolds for the engineering of musculoskeletal tissue (including bone, cartilage, ligament, and skeletal muscle), skin, vascular, and neural tissue. This article examines the usage of nanofibers in tissue engineering and drug delivery applications as well as the current methods for synthesizing them.

Keyphrases: Bioengineering, Nanofibers, tissue engineering

@booklet{EasyChair:13284,
  author    = {Harsul Thakur},
  title     = {Nanofibers and Their Applications in Tissue Engineering},
  howpublished = {EasyChair Preprint 13284},
  year      = {EasyChair, 2024}}