Bio-Microfluidic Systems: Integration and Functionalities for Point-of-Care Diagnostics

EasyChair Preprint no. 11471

Abstract

Bio-microfluidic systems have emerged as versatile platforms in the realm of point-of-care diagnostics, offering integration and functionalities that revolutionize healthcare delivery. These systems, employing the manipulation of fluids at a microscale, combine biology, physics, and engineering principles to enable precise control and analysis of biological samples. This paper explores the integration and functionalities of bio-microfluidic systems for point-of-care diagnostics. It investigates the diverse approaches employed in designing these systems, encompassing microfluidic channels, valves, pumps, and sensors that facilitate the manipulation and analysis of minute sample volumes. Furthermore, it delves into the integration of biological components, such as cells, proteins, and nucleic acids, within these platforms to enable a broad spectrum of diagnostic capabilities. Moreover, this paper discusses the diverse functionalities offered by bio-microfluidic systems, including rapid and sensitive detection of biomarkers, infectious agents, and genetic variations. The review also examines the challenges and future directions in the development and deployment of bio-microfluidic systems for point-of-care diagnostics. It explores ongoing research efforts aimed at enhancing sensitivity, specificity, and usability while addressing issues related to standardization, cost-effectiveness, and regulatory compliance.

Keyphrases: Bio-Microfluidic Systems, Microfluidics, Point-of-care diagnostics

@Booklet{EasyChair:11471,
  author = {Lee Kasowaki and Rhys Clark},
  title = {Bio-Microfluidic Systems: Integration and Functionalities for Point-of-Care Diagnostics},
  howpublished = {EasyChair Preprint no. 11471},

  year = {EasyChair, 2023}}