In Vitro and in Vivo Assessment of Q203 and PBTZ169 Combination: Implications for Tuberculosis Therapy

EasyChair Preprint 11875

Abstract

This study provides a dual-focused investigation into the combination of Q203 and PBTZ169, aiming to assess their synergistic potential for tuberculosis therapy. In vitro experiments employed the checkerboard method, establishing the fractional inhibitory concentration index (FICI) to gauge the interaction effects of these compounds. Results revealed a synergistic relationship, suggesting enhanced antibacterial efficacy when Q203 and PBTZ169 are combined. The outcomes presented in this study serve as a foundation for future research endeavors and advancements in the field of tuberculosis therapy.

Keyphrases: Efficacy, abc, antimycobacterial

@booklet{EasyChair:11875,
  author    = {Kurez Oroy and Jack Liu},
  title     = {In Vitro and in Vivo Assessment of Q203 and PBTZ169 Combination: Implications for Tuberculosis Therapy},
  howpublished = {EasyChair Preprint 11875},
  year      = {EasyChair, 2024}}