Cellular Mechanisms of Bone Regeneration in Xenograft Applications

EasyChair Preprint 13172

Abstract

Xenograft materials derived from natural sources, such as bovine or porcine bone, have been extensively utilized in bone regeneration procedures due to their biocompatibility and osteoconductive properties. This review focuses on elucidating the cellular mechanisms underlying bone regeneration in xenograft applications.

A comprehensive analysis of the literature was conducted to identify studies investigating the cellular responses to xenograft materials during bone regeneration. Key cellular mechanisms, including osteoinduction, osteoconduction, and angiogenesis, were examined in detail.

The findings highlight the crucial role of osteoblasts, osteoclasts, and mesenchymal stem cells in the process of bone formation and remodeling following xenograft implantation. Xenograft materials serve as scaffolds for cell attachment, proliferation, and differentiation, thereby promoting new bone formation.

Keyphrases: Biomaterials, Cellular Mechanisms, Osteoclasts, Osteogenesis, Scaffold, Transplantation Biology, biocompatibility, bone regeneration, extracellular matrix, growth factors, host response, osteoblasts, regenerative medicine, tissue engineering, xenograft

@booklet{EasyChair:13172,
  author    = {Abill Robert and Dylan Stilinski},
  title     = {Cellular Mechanisms of Bone Regeneration in Xenograft Applications},
  howpublished = {EasyChair Preprint 13172},
  year      = {EasyChair, 2024}}