Download PDFOpen PDF in browserUnlocking the Secrets: Identifying Critical Structural Components in Hsp90 Alpha Inhibitors for Enhanced Cancer TreatmentEasyChair Preprint 116756 pages•Date: January 3, 2024AbstractThe search for effective cancer treatments has led to the exploration of targeted therapies, with inhibitors of the Heat Shock Protein 90 (Hsp90) alpha isoform emerging as promising candidates. This study delves into the intricate world of Hsp90 alpha inhibitors, seeking to identify and elucidate the critical structural components that underlie their enhanced efficacy in cancer treatment. Employing a multi-faceted approach that integrates computational modeling, structural analysis, and experimental validation, we unravel the secrets hidden within the molecular architecture of Hsp90 alpha inhibitors. By dissecting the three-dimensional structures and elucidating the intermolecular interactions, we identify specific structural components that play a pivotal role in augmenting the therapeutic potential of these inhibitors. Keyphrases: Inhibitors, cancer, treatment
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